Antimycobacterial activity of novel camphane based isoindoline

personАвтори: G. Dobrikov, G.Stavrakov, V. Valcheva

Summary: A new isoindoline containing amino-alcohol was synthesised on the base of the camphor scaffold and evaluated for its in vitro activity against M. tuberculosis H37Rv. The compounds shows activity comparable with the one of the classical anti-TB drug ethambutol. The camphane-based structures present novel promising scaffolds for antimycobacterial agents.

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