Synthesis and antimycobacterial activity of novel mandelic acid derived diamide

personАвтори: G.Stavrakov, I. Philipova, V. Valcheva

Summary A new mandelic acid derived diamido-diol was synthesised on the base of (1R,2R)-1,2-diaminocyclohexane scaffold and evaluated for its in vitro activity against M. tuberculosis H37Rv. The compound shows activity comparable with the one of the classical anti-TB drug ethambutol.

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