Abstract For UV filter of Octocrylene, as a component of cosmetic products, there exists a maximum applicable concentration indicated in legislation up to 10%. The observation of the mandatory limits has to be strictly controlled. On the other hand, the establishment of real content of the UV filter lower than the declared in cosmetic formulation is an indication for lack of safety protection against UV filters declared on the label. There is no referent method for determination of UV filter of Octocrylene in sunscreen products. The aim of this study is to develop and validate a useful spectrophotometric method for its determination. There has been developed and validated a spectrophotometric method for determination of UV filter of Octocrylene in sunscreens, which is applied  both singularly and in combination with physical filters of Zinc Oxide and Titanium Dioxide. The method is based on the capacity of solutions of Octocrylene in ethanol to absorb UV filters with wave length of 305 nm. The value of light absorption measured at this wave length is proportional to the concentration of Octocrylene. A total of 278 studies were performed, on the basis of which, the parameters derived of the method are: selection – specific absorption at 303 nm; linearity from 2,5 to 80 μg/cm³ (from 1,25% to 40,0%); stability for 24-hour duration at concentration of Octocrylene 10 μg/cm³ – RSD = 0,38%; repeatability – by 4% of Octocrylene – SD – 0,0356%; reproducibility – by 4% of Octocrylene – RSD under conditions of repeatability – 0,94%; yield at concentration of Octocrylene in cosmetic product by 2% – 96,56% (94,00% – 99,25%), by 4% -95,71% (94,13% – 98,38%). For the different types of cosmetic products there have been established: working range – from 0,75% to 40%, limit of detection (LOD) – from 0,60% to 2,50%, limits of quantification (LOQ) – from 0,75% to 2,67%. The spectrophotometric method developed and validated for determination of UV filter of Octocrylene in sunscreen products is fast, sensitive, of good accuracy and reproducibility does not require sophisticated and expensive apparatuses. It can be applied easily for the control of sunscreen cosmetic products.