Overview of the oncopharmacological studies of plant-derived natural products conducted at the Faculty of Pharmacy (MU-Sofia)

personАвтори: Dimitrina Zheleva-Dimitrova, Georgi Momekov, Gerassim Kitanov, Iliana Ionkova, Ilina Dineva, Ilina Krasteva, Niko Benbassat, Paraskev Nedialkov, Spiro Konstantinov, Stefan Nikolov, Yohana Ilieva, Zlatina Kokanova-Nedialkova

Abstract. The present review gives an outline of some oncopharmacological projects focused on the characterization of plant-derived natural products, conducted at the Faculty of Pharmacy at the Medical University of Sofia. These include collaborative phytochemical/pharmacological studies of a) alkaloids, b) saponines with immunomodulatory and anti-cancer effects; c) cytotoxic lignans; iii) phenolic compounds (acylphloroglucinols, benzophenones, xanthones) from Hypericum spp.  iv) various volatiles and crude extracts.

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